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Pathology Research International
Volume 2014 (2014), Article ID 678628, 9 pages
Research Article

A Prospective Study of Soft Tissue Tumors Histocytopathology Correlation

1Department of Pathology, Deen Dayal Upadhyay Hospital, Hari Nagar, New Delhi 110066, India
2Department of Pathology, Employees’ State Insurance Scheme of India (ESI) Hospital, Basaidarapur, New Delhi 110015, India
3Department of Pathology, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh 245304, India

Received 31 January 2014; Accepted 12 April 2014; Published 28 April 2014

Academic Editor: Oscar W. Cummings

Copyright © 2014 Priyanka Bhatia Soni et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Soft tissue tumors are defined as nonepithelial extraskeletal tissue of the body exclusive of the reticuloendothelial system, glia, and supporting tissue of various parenchymal organs. The absence of recognizable tissue architectural patterns in cytological preparation makes diagnosis by FNAC more difficult. Aims. To assess the utility of FNAC in diagnosing soft tissue tumors and to determine their patterns compared with with the respective histopathology results. Materials and Methods. 150 cases of soft tissue tumors were included in this study for cytologic and histologic correlation. FNAC air dried smears were stained with Giemsa stain and 95% ethanol fixed smears were stained with Papanicolaou stain. The smears were studied for cytological diagnosis and were categorized as benign, suspicious of malignancy, and malignant along with specific subtyping of the lesion. All diagnostic FNAC results were compared for diagnostic concordance using histology results as the “gold standard.” Results. The sensitivity, specificity, positive predictive value, negative predictive value, and efficiency were 70%, 100%, 97.90%, 100%, and 98%, respectively. value was 0.0001 which shows statistically extreme significant correlation. Conclusion. FNAC is a very important preliminary diagnostic tool in palpable soft tissue lumps with high degree of correlation with the final histopathology report.