A Prospective Study of Soft Tissue Tumors Histocytopathology Correlation
Figure 3
(a) Well differentiated liposarcoma: lipoblasts with atypical hyperchromatic nuclei and multinucleated giant cell (H&E ×100, ×400 inset). (b) Malignant mesenchymal lesion (low grade fibromyxoid sarcoma) cytology: loosely arranged bland spindle cells with slight to moderate atypia arranged in a myxoid background (Giemsa ×100). (c) Low grade fibromyxoid sarcoma: abrupt transition from fibrous areas (composed of bland spindle cells) to myxoid areas (H&E ×100). (d) Malignant mesenchymal lesion (malignant fibrous histiocytoma) cytology: bizarre tumor cells with prominent nucleoli (Giemsa ×400). (e) Malignant fibrous histiocytoma: cells with marked pleomorphism and mitosis (H&E ×400). (f) Malignant mesenchymal lesion (clear cell sarcoma) cytology: atypical spindle to oval cells entangled in stroma. (Giemsa × 400). (g) Clear cell sarcoma: Tumor cells in short fascicles separated by dense fibrous septa exhibiting prominent vesicular nuclei with large single nucleolus (H&E ×400). (h) Malignant mesenchymal lesion (alveolar soft part sarcoma) cytology: spindle to epithelioid cells with prominent nucleoli and high N : C ratio (Giemsa ×100, inset ×400). (i) Alveolar soft part sarcoma: tumor cells in typical organoid/nesting pattern are separated by delicate partitions of connective tissue containing vascular channels (H&E ×100) with chunky crystalline inclusions (inset) (PAS × 400).
