Immunohistochemical Investigation of HER/AKT/mTOR Pathway and Cellular Adhesion Molecules in Urothelial Carcinomas

Figure 2

CAM expression in different urothelial tumors. A case of noninfiltrative high grade urothelial carcinoma positive for e-cadherin (a), p-cadherin (b), and b-catenin (c) markers, in contrast to high grade infiltrative urothelial carcinoma with sarcomatoid features, exhibited no or weak expression in few cells to e-cadherin (d), p-cadherin (e), and b-catenin (f) antibodies ((a–f) IHC ×400).

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(b)

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(d)

(e)

(f)