Immunohistochemical Investigation of HER/AKT/mTOR Pathway and Cellular Adhesion Molecules in Urothelial Carcinomas

Table 2

Immunohistochemical distribution of the examined markers.

		%
HER2
0	8	19.5
1+	14	34.1
2+	11	26.8
3+	8	19.6
EGFR
Negative	27	65.9
Positive	14	34.1
pAKT nuclear
Negative	17	41.5
Positive	24	58.5
pAKT cytoplasmic
Negative	29	70.7
Positive	12	29.3
PTEN cytoplasmic
Negative	19	47.5
Positive	21	52.5
Missing data	1	—
PTEN nuclear
Negative	31	77.5
Positive	9	22.5
Missing data	1	—
PTEN nuclear/cytoplasmic
Negative	10	25
Positive	30	75
Missing data	1	—
pmTOR
Negative	19	46.3
Positive	22	53.7
MIB1
≤20	23	56.1
>20	18	43.9
e-cadherin
Negative	16	45.7
Positive	19	54.3
Missing data	6	—
p-cadherin
Negative	20	58.8
Positive	14	41.2
Missing data	7	—
b-catenin
Negative	10	28.6
Positive	25	71.4
Missing data	6	—