Research Article

Accelerated Blood Clearance (ABC) Phenomenon Favors the Accumulation of Tartar Emetic in Pegylated Liposomes in BALB/c Mice Liver

Table 1

Mean size, polydispersity index, zeta potential, and drug encapsulation efficiency. Results are represented as mean ± SD.

Mean diameter (nm)Polydispersity indexZeta potential (mV)Drug encapsulation efficiency (%)

Lpeg + tartar emetic177.1 ± 0.90.07 ± 0.01−2.59 ± 0.314%
Blank Lpeg191.6 ± 1.60.06 ± 0.01−4.87 ± 0.9
Lconv+ tartar emetic
197.3 ± 1.00.09 ± 0.03−12.9 ± 1.713.5%
Blank Lconv207.3 ± 0.40.09 ± 0.01−10.2 ± 0.9