Pathology Research International

Pathological and Immunological Developments in Behcet’s Disease


Publishing date
15 Mar 2012
Status
Published
Submission deadline
15 Sep 2011

Lead Editor

1Department of Dermatology, University of Mersin School of Medicine, Mersin, 33079, Turkey

2Dermatologie Afdelingen, Bovenij Ziekenhuis, Postbus 37610, 1030 BD Amsterdam, The Netherlands

3Department of Dermatology, University of Florence, Via della Pergola 60, 50132 Florence, Italy

4Rheumatology Research Center, Shariati Hospital, Kargar Avenue, Tehran, Iran


Pathological and Immunological Developments in Behcet’s Disease

Description

Behcet disease is a rare form of vasculitis that may have systemic multiorgan involvement. Behçet's disease was first defined by Hulusi Behçet, a Turkish Professor of dermatology, in 1937 as a triad of recurrent aphthous stomatitis, genital aphthae, and relapsing uveitis. As this disease can be fatal, an immediate medical treatment is mandatory. So far there is no specific pathological testing or technique available for the diagnosis of the disease, although the International Study Group criteria for the disease are of good sensitivity and specificity. However, quite a portion of patients are misdiagnosed or have been delayed diagnosis. During the ensuing 65 years, multiple systemic associations of the disease including articular, vascular, gastrointestinal, cardiopulmonary, and neurologic involvement have become increasingly apparent. Although the etiology and pathogenesis is not clearly defined, genetic predisposition, infections, and immunological dysfunctions have been implicated. Behcet's disease has been reported worldwide, but has a distinct geographic distribution, with highest prevalences in countries along the ancient silk route. Although much has been learned during recent years on the pathogenesis and treatment of the disease, it is still an important cause of morbidity and mortality in areas where it is prevalent. Potential topics include, but are not limited to:

  • Development and testing relevant investigations on Behcet's disease
  • Genetic susceptibilities of Behçet's disease
  • Development of immunopathogenesis strategies to treat Behcet's disease
  • Elucidating the role of stress factors and stress hormones in the development of Behcet's disease
  • Identification of new different skin lesions and histopathological results in Behcet's disease
  • New diagnostic criteria in Behcet's disease (diagnostic/classification criteria for Behcet's disease)
  • New animal models to test and understand immunopathogenesis of Behcet's disease
  • New evidence-based treatment approach in Behcet's disease
  • Osteoporosis and rare musculosceletal findings in Behçet's disease
  • Clinical and pathological manifestations with differential diagnosis in Behçet's disease
  • Pathologic features of Behcet's disease in the tubular gut
  • Diagnostic/Classification criteria for Behcet's Disease

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/pri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 305780
  • - Editorial

Pathological and Immunological Developments in Behcet's Disease

Umit Tursen | Gamze Piskin | ... | Fereydoun Davatchi
  • Special Issue
  • - Volume 2012
  • - Article ID 261989
  • - Review Article

Development of Immunopathogenesis Strategies to Treat Behçet’s Disease

Osman Köse
  • Special Issue
  • - Volume 2012
  • - Article ID 273701
  • - Review Article

Animal Models in Behçet's Disease

Ozlem Yildirim
  • Special Issue
  • - Volume 2012
  • - Article ID 595380
  • - Review Article

Potential Infectious Etiology of Behçet's Disease

Massimiliano Galeone | Roberta Colucci | ... | Torello Lotti
  • Special Issue
  • - Volume 2012
  • - Article ID 827815
  • - Review Article

Behcet's Disease and Endocrine System

Onur Ozhan | Kerem Sezer
  • Special Issue
  • - Volume 2012
  • - Article ID 690390
  • - Review Article

Clinical and Pathological Manifestations with Differential Diagnosis in Behçet's Disease

Aysin Kokturk
  • Special Issue
  • - Volume 2012
  • - Article ID 216254
  • - Review Article

Pathologic Features of Behçet's Disease in the Tubuler Gut

Tuba Kara | Duygu Düşmez Apa
  • Special Issue
  • - Volume 2012
  • - Article ID 209316
  • - Review Article

Histopathological Evaluation of Behçet's Disease and Identification of New Skin Lesions

Özgür Gündüz
  • Special Issue
  • - Volume 2012
  • - Article ID 912589
  • - Review Article

Genetics of Behçet's Disease

Tamer İrfan Kaya
  • Special Issue
  • - Volume 2012
  • - Article ID 871019
  • - Review Article

New Evidence-Based Treatment Approach in Behçet's Disease

Erkan Alpsoy

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