Central nervous system (CNS) infections are uncommon but tend to have potentially serious consequences. Though well protected by overlying skin, soft tissue and bone, as well as the blood brain barrier, the CNS remains vulnerable to many infectious agents. With the changing face of modern medicine, there are changes in the epidemiology of bacterial infections and the incidence of fungal infections, and there has been a resurgence of old infectious agents and an emergence of new infections. The identification of predisposing risk factors and gaining an increased understanding of the pathogenesis and pathology of CNS infections will lead to the development and application of more effective therapeutic strategies. Furthermore, the early and accurate diagnoses are essential in predicting prognosis.

We invite original research articles as well as review articles describing the recent advances in the pathology and pathogenesis, laboratory, and molecular diagnostic methods of various CNS infections. Potential topics include, but are not limited to:

• Epidemiology of CNS infections
• Clinical and imaging features in the diagnosis of CNS infections
• Neurotuberculosis
• Brain abscesses: new pathogens and diagnostic challenges
• Fungal infections of CNS
• HIV and CNS pathology
• Molecular epidemiology of HIV with reference to NeuroAIDS
• Laboratory diagnosis of CNS infections
• Molecular diagnostic methods for the diagnosis of CNS infections
• Pathology of Prion diseases
• Rabies encephalitis and Measles encephalitis
• CNS neoplasms associated with chronic viral infections
• Brain banking for CNS infections

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/pri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: