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Pain Research and Management
Volume 19, Issue 6, Pages e154-e158
http://dx.doi.org/10.1155/2014/314910
Original Article

Does Low-Level Laser Therapy Enhance The Efficacy of Intravenous Regional Anesthesia?

Sholeh Nesioonpour,1,2 Reza Akhondzadeh,1,2 Soheila Mokmeli,3 Shahnam Moosavi,4 Mandana Mackie,1,2 and Morteza Naderan5

1Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2Department of Anesthesiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3Canadian Optic & Laser Production Center, British Columbia, Canada
4Department of Orthopedics, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
5Farzan Clinical Research Institute, Tehran, Iran

Copyright © 2014 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

BACKGROUND: The use of intravenous regional anesthesia (IVRA) is limited by pain resulting from the application of tourniquets and postoperative pain.

OBJECTIVE: To assess the efficacy of low-level laser therapy added to IVRA for improving pain related to surgical fixation of distal radius fractures.

METHODS: The present double-blinded, placebo-controlled, randomized clinical trial involved 48 patients who were undergoing surgical fixation of distal radius fractures. Participants were randomly assigned to either an intervention group (n=24), who received 808 nm laser irradiation as 4 J/point for 20 s over ipsilateral three nerve roots in the cervical region corresponding to C5–C8 vertebrae, and 808 nm laser irradiation as 0.1 J/cm2 for 5 min in a tangential scanning mode over the affected extremity; or a control group (n=24), who underwent the same protocol and timing of laser probe application with the laser switched off. Both groups received the same IVRA protocol using 2% lidocaine.

RESULTS: The mean visual analogue scale scores were significantly lower in the laser-assisted group than in the lidocaine-only group on all measurements during and after operation (P<0.05). The mean time to the first need for fentanyl administration during the operation was longer in the laser group (P=0.04). The total amount of fentanyl administered to patients was significantly lower in the laser-assisted group (P=0.003). The laser group needed significantly less pethidine for pain relief (P=0.001) and at a later time (P=0.002) compared with the lidocaine-only group. There was no difference between the groups in terms of mean arterial pressure and heart rate.

CONCLUSION: The addition of gallium-aluminum-arsenide laser irradiation to intravenous regional anesthesia is safe, and reduces pain during and after the operation.