Clinical Study

Effect of N-Methyl-D-Aspartate Receptor Antagonist Dextromethorphan on Opioid Analgesia in Pediatric Intensive Care Unit

Table 3

Primary outcome in RCT. Comparison of dose(s) of fentanyl in groups. Groups compared via Student’s t-test for comparison of means. is significant. Values are expressed as mean and standard deviation.

Dose(s)Group 1: dextromethorphan µ gram/kg/96 hrs
(number: 16)
Group 2: placebo µ gram/kg/96 hrs (number: 13) value

Cumulative
 Mean217.942680.127
 Std Dev87.781.84
 SEM21.922.7
Infusion
 Mean215.63256.690.257
 Std Dev89.27101.6
 SEM22.3228.2
PRN
 Mean2.313.620.101
 Std Dev2.211.85
 SEM0.550.51