Relationship between Neuropathic Pain and Obesity

Table 1

Clinical characteristics of the participants.

Variable	Overweight ()	Normal-weight ()	value
Age (year)	57.3 (41.3–69.8)	61.7 (54.0–74.0)	0.39
Sex (male/female)	9/5	19/11	0.95
Height (m)	1.67 (1.55–1.77)	1.64 (1.58–1.69)	0.23
Weight (kg)	82.4 (65.9–99.0)	58.4 (52.5–65)	<0.0001
BMI (kg/m^2)	29.4 (25.9–32.5)	21.7 (20.5–23.4)	<0.0001
Disease duration (month)	89.1 (24–175)	51.1 (13–64.5)	0.19
Pregabalinoids (mg/kg/day)	4.6 (0–6.4)	4.1 (0–7.1)	0.66
Tricyclic antidepressants (mg/kg/day)	0.11 (0–0.32)	0.03 (0–0)	0.06
Opioids (mg/kg/day)	0.25 (0–0.017)	0.59 (0–1.25)	0.12

Data are expressed as medians (25th percentile–75th percentile). Weight categories are defined using the Federal Obesity Guidelines established by the National Heart, Lung, and Blood Institute: normal (BMI between 18.5 and 25 kg/m²), overweight (BMI more than 25 kg/m²), and underweight (BMI less than 18.5 kg/m²). Underweight patients were excluded from the statistical analyses because of their limited number. The data for the specific medications indicate the daily-dose per weight (mg/kg).
BMI: body mass index.
values are derived using the Mann-Whitney test or the chi-square test for data with skewed distribution.