Research Article

Relationship between Neuropathic Pain and Obesity

Table 2

Impact of body-weight on pain intensity, patient-reported symptoms, and quality of life.

VariableOverweight ()Normal-weight () value

NRS7.4 (6.5–9.3)5.8 (3.8–8.0)0.04

NPSI total score54.5 (40.3–75.0)39.9 (25.0–59.8)0.03
Burning (superficial)5.6 (3.5–8.0)4.2 (0.8–7.0)0.15
Spontaneous pain (deep)3.5 (0.0–5.3)3.1 (0.0–5.1)0.62
 Squeezing3.7 (0.0–7.3)3.3 (0.0–6.0)0.73
 Pressure3.3 (0.0–6.0)2.8 (0.0–5.0)0.50
Paroxysmal pain3.6 (0.0–5.5)1.9 (0.0–4.0)0.049
 Electric shocks4.6 (0.0–8.3)2.3 (0.0–4.8)0.05
 Stabling2.6 (0.0–7.0)1.6 (0.0–3.3)0.31
Evoked pain4.5 (2.0–6.8)3.2 (0.5–5.8)0.20
 Brush-evoked pain4.6 (0.8–8.0)3.3 (0.0–7.3)0.23
 Pressure-evoked pain4.7 (1.5–8.0)3.5 (0.0–7.0)0.27
 Cold-evoked pain4.3 (1.5–6.5)2.9 (0.0–5.0)0.17
Paresthesia and dysesthesia6.6 (4.8–8.5)5.1 (3.5–7.1)0.06
 Tingling7.7 (7.3–10.0)6.3 (4.0–8.0)0.06
 Pins and needles5.4 (2.3–8.0)3.8 (0.0–7.0)0.16

SF-MPQ total21.1 (15.5–25.5)15.3 (8.0–20.0)0.049
 Sensory dimension13.9 (8.0–19.0)10.7 (5.8–15.0)0.12
 Affective dimension7.1 (5.0–9.3)4.6 (1.8–7.3)0.03

SF-36
 PCS32.0 (19.0–41.9)32.9 (20.9–45.7)0.57
 MCS43.2 (37.2–46.1)44.2 (34.2–55.4)0.72
 RCS36.7 (21.1–51.4)36.8 (27.8–48.2)0.80

Data are expressed as medians (25th percentile–75th percentile). NRS: an 11-point numerical rating scale; BMI: body mass index; NPSI: Neuropathic Pain Symptom Inventory; SF-MPQ: Short-Form McGill Pain Questionnaire; SF-36: Short Form-36 health survey; PCS: pain component summary; MCS: mental component summary; RCS: role/social component summary.