Depressed Mood Differentially Mediates the Relationship between Pain Intensity and Pain Disability Depending on Pain Duration: A Moderated Mediation Analysis in Chronic Pain Patients
Table 4
Results of the moderated mediation analysis investigating pain duration as a moderator of the direct effect of pain intensity on pain disability and as a moderator of the indirect effect of pain intensity on pain disability through depressed mood.
(a) Consequent
Antecedent
Depressed mood (mediator)
Pain disability (outcome)
Coeff.
SE
Coeff.
SE
Pain intensity (predictor)
−.21
.49
.67
2.43
.56
<.01
Pain duration (moderator)
−.07
.03
.04
.03
.04
.42
Pain intensity pain duration
.01
<.01
.01
<.01
.01
.95
Depressed mood (mediator)
—
—
—
.55
.09
<.01
Depressed mood pain duration
—
—
—
<.01
<.01
.22
(b) Conditional direct effects of pain intensity on pain disability
Pain duration (percentiles)
Effect
SE
LLCI
ULCI
12 months
2.44
.51
4.79
<.01
1.44
3.44
24 months
2.44
.47
5.24
<.01
1.53
3.36
60 months
2.45
.38
6.43
<.01
1.70
3.20
120 months
2.47
.45
5.46
<.01
1.58
3.36
204 months
2.50
.81
3.07
<.01
.90
4.10
(c) Conditional indirect effects of pain intensity on pain disability through depression
Pain duration (percentiles)
Effect
Boot SE
Boot LLCI
Boot ULCI
Effect size
12 months
−.04
.22
−.49
.39
−0.02
24 months
.03
.20
−.37
.43
0.01
60 months
.24
.16
−.06
.56
0.09
120 months
.51
.18
.22
.94
0.17
204 months
.77
.41
.14
1.80
0.23
Note. Coeff.: coefficient; SE: standard error; LLCI: lower level of the 95% confidence interval; ULCI: upper level of the 95% confidence interval; percentiles: 10th, 25th, 50th, 75th, and 90th percentiles; effect size: ratio of the indirect effect to the total effect.