Review Article

Development of Cardiovascular Indices of Acute Pain Responding in Infants: A Systematic Review

Table 4

Mean and standard deviations for heart rate change from baseline in response to acute pain at less than 7 postnatal days.

Gestational ageReferenceHR changeSD

28–32 weeksGoubet et al. [44]0–15 bpmN/A

37–42 weeksAltun-Köroğlu et al. [35]37.00%N/A
Bilgen et al. [36]19.00%N/A
Bucher et al. [37]45 bpmN/A
Gray et al. [45]36–38 bpmN/A
Haouari et al. [47]11.40% 3.0
Jatana et al. [48]31.48 bpm6.66 bpm
Ors et al. [60]19.00%N/A
Owens and Todt [61]49.00 bpm17.5 bpm
Sajedi et al. [62]10.81 N/A
Uyan et al. [68]38.20%N/A
Weissman et al. [70]36.50 bpm19.50 bpm

Note. denotes numbers that were extrapolated from graphs.