Research Article

Noradrenaline, Serotonin, GABA, and Glycine in Cerebrospinal Fluid during Labor Pain: A Cross-Sectional Prospective Study

Table 1

Demographic, anthropometric, and clinical characteristics of pregnant women in the control and labor pain groups.

Control
group
()
Labor pain group
()
value

Age (years), mean ± SD
Weight (kg), mean ± SD0.9
Height (cm), mean ± SD0.3
Body mass index (kg/m2), mean ± SD0.58
Gestational age (weeks), mean ± SD0.88
Indication for C/S, (%)
 (i) CPD13 (30.22%)31 (68.90%)
 (ii) Previous C/S23 (53.49%)10 (22.22%)
 (iii) Malrotation of fetus5 (11.63%)4 (8.88%)
 (iv) Twins1 (2.33%)0 (0%)
 (v) Previous surgery1 (2.33%)0 (0%)
Preoperative pain score (NRS), median (IQR) (P25–P75)0 (0-0)9 (7–10)
 (i) Number of patients, NRS 5, (%)0 (0%)0 (0%)
 (ii) Number of patients, NRS 6, (%)0 (0%)8 (17.78%)
 (iii) Number of patients, NRS 7, (%)0 (0%)4 (8.88%)
 (iv) Number of patients, NRS 8, (%)0 (0%)9 (20.00%)
 (v) Number of patients, NRS 9, (%)0 (0%)8 (17.78%)
 (vi) Number of patients, NRS 10, (%)0 (0%)16 (35.56%)
Pain duration (minutes), median (IQR) (P25–P75)0 (0-0)325 (240–525)
Preoperative pain treatment, (%)
 (i) No treatment43 (100%)28 (62.22%)
 (ii) Received pain medication0 (0%)17 (37.78%)
Dose of pethidine administration, (%)
 (i) 50 mg IM0 (0%)13 (28.89%)
 (ii) 75 mg IM0 (0%)4 (8.89%)

value < 0.05 indicates statistical significance. CPD, cephalopelvic disproportion; C/S, cesarean section; IM, intramuscular; IQR, interquartile range; NRS, numerical rating scale; P, percentile; SD, standard deviation.