Research Article
Pregabalin Prescription for Neuropathic Pain and Fibromyalgia: A Descriptive Study Using Administrative Database in Japan
Table 2
Prescription patterns according to gender and age.
| | | | Initial daily dose | Maximum daily dose | Prescription period | | N (%) | Mean (SD) | Mean (SD) | Mean (SD) | Median (25, 75 percentile) | | Age | | <65 | ≥65 | <65a | ≥65 | value | <65 | ≥65 | value | <65 | ≥65 | value | <65 | ≥65 | value |
| | Sex | | | | | | | | | | | | | | | | Male | 8578 (50.8) | 13507 (47.5) | 110.6 (57.8) | 98.0 (58.4) | <0.001 | 149.7 (97.2) | 130.4 (88.9) | <0.001 | 104.7 (118.4) | 118.8 (126.5) | <0.001 | 49 (21,144) | 57 (22,184) | <0.001 | | Female | 8318 (49.2) | 14928 (52.5) | 101.9 (55.2) | 86.6 (53.2) | <0.001 | 132.3 (85.3) | 110.2 (75.7) | <0.001 | 100.5 (118.0) | 116.2 (128.1) | <0.001 | 43 (16,132) | 54 (21,178) | <0.001 |
| | Initial daily dose | | | | | | | | | | | | | | | | <50 mg | 1470 (8.7) | 4267 (15.0) | — | — | — | 55.7 (55.6) | 51.4 (54.7) | 0.001 | 112.4 (124.5) | 130.1 (132.2) | <0.001 | 56 (21,161) | 63 (27,225) | <0.001 | | ≥50 mg, <75 mg | 2714 (16.1) | 5977 (21.0) | — | — | — | 86.2 (66.7) | 78.8 (54.0) | <0.001 | 113.5 (122.5) | 126.9 (129.1) | <0.001 | 56 (24,164) | 65 (28,205) | <0.001 | | ≥75 mg, <150 mg | 4886 (28.9) | 8253 (29.0) | — | — | — | 116.2 (71.6) | 109.8 (67.4) | <0.001 | 98.4 (114.7) | 117.3 (127.4) | <0.001 | 44 (20,127) | 56 (21,182) | <0.001 | | ≥150 mg | 7826 (46.3) | 9938 (34.9) | — | — | — | 191.9 (86.9) | 182.2 (76.4) | <0.001 | 99.7 (117.4) | 106.5 (123.0) | <0.001 | 42 (14,135) | 46 (16,149) | 0.013 |
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