Research Article

Chemical Composition and Antioxidant, Analgesic, and Anti-Inflammatory Effects of Methanolic Extract of Euphorbia retusa in Mice

Figure 4

(a) The paw of mice treated with carrageenan and/or indomethacin or the methanolic extract of Euphorbia retusa. (b) Percentage inflammation of the paws of mice induced by local injection of carrageenan and/or indomethacin or the methanolic extract of Euphorbia retusa. Control: normal mice injected with isotonic saline solution (NaCl) 0.9%; Carr: mice injected with carrageenan 1%; Carr + Indo: mice pretreated with indomethacin and injected with carrageenan; Carr + Eu: mice pretreated with the methanolic extract of E. retusa and injected with carrageenan. (c) Percent inhibition of paw edema in mice pretreated with the Euphorbia retusa extract and indomethacin, induced after local injection of carrageenan. Values are represented as mean ± SD () in each group. . p: compared with the control; +p: compared with carrageenan.
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