Chemical Composition and Antioxidant, Analgesic, and Anti-Inflammatory Effects of Methanolic Extract of Euphorbia retusa in Mice

Table 5

Effect of carrageenan on antioxidant enzyme activities in liver and paw tissues of mice.

	Liver			Paw
	SOD	CAT	GPx	SOD	CAT	GPx
Control	12.83 ± 2.67	1.94 ± 0.20	77.40 ± 4.63	20.08 ± 1.04	0.14 ± 0.01	70.32 ± 3.73
Carr	6.48 ± 0.28	0.53 ± 0.18	22.54 ± 4.92	8.66 ± 0.93	0.04 ± 0.01	12.23 ± 3.32
Carr + Indo	12.19 ± 0.35^+++	1.45 ± 0.24^+	54.74 ± 4.66^+++	17.90 ± 1.23^+++	0.12 ± 0.01^+	44.75 ± 2.95^+++
Carr + Eu	10.60 ± 0.52^+++	0.89 ± 0.24^+	45.35 ± 1.91^+++	16.79 ± 1.06^+++	0.10 ± 0.01^+	26.73 ± 3.08^+++

CAT: µmol of H₂O₂ destroyed/min/mg of protein; SOD: U/mg protein; GPx: µmol of NADPH oxidized/min/mg of protein. Values are expressed as mean ± SD of six mice in each group. Carr group versus control group: . Carr + Indo or Carr + Eu group versus Carr group: . Carr: carrageenan; Indo: Indomethacin; Eu: Euphorbia retusa.