Research Article

Evoked and Ongoing Pain-Like Behaviours in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy

Figure 3

Time course of paclitaxel-induced cold hypersensitivity. Graph shows the median ± interquartile range of the hind paw response to acetone application catergorised by the cold score. BL = baseline before paclitaxel/vehicle administration. Arrows indicate four injections of 2 mg/kg paclitaxel or equivalent volume of vehicle on days 0, 2, 4, and 6. , the Friedman test with Dunn’s post hoc test comparing the baseline scores in each group ( per group). As this analysis is nonparametric, the error bars appear larger than expected from parametric analysis.