The Mediating Effect of Central Sensitization on the Relation between Pain Intensity and Psychological Factors: A Cross-Sectional Study with Mediation Analysis
Table 2
Mediation analysis: the role of CSI as a mediator.
Path/effect
β
SE
value/95% BCCI
a HADS-anxiety ⟶ CSI
0.659
0.522
0.002
b CSI ⟶ SFMPQ2-total
0.496
0.632
0.043
c (direct effect) HADS-anxiety ⟶ SFMPQ2-total
0.277
1.861
0.239
c′ (total effect) HADS-anxiety ⟶ SFMPQ2-total
0.604
1.540
0.005
a × b (indirect effect) HADS-anxiety ⟶ SFMPQ2-total
0.327
1.729
(LL = 0.208, UL = 7.176)
a HADS-depression ⟶ CSI
0.578
0.655
0.008
b CSI ⟶ SFMPQ2-total
0.559
0.592
0.018
c (direct effect) HADS-depression ⟶ SFMPQ2-total
0.206
2.015
0.345
c′ (total effect) HADS-depression ⟶ SFMPQ2-total
0.530
1.896
0.016
a × b (indirect effect) HADS-depression ⟶ SFMPQ2-total
0.323
1.501
(LL = 0.714, UL = 6.780)
a PCS ⟶ CSI
0.537
1.252
0.015
b CSI ⟶ SFMPQ2-total
0.414
0.485
0.029
c (direct effect) PCS ⟶ SFMPQ2-total
0.492
3.053
0.012
c′ (total effect) PCS ⟶ SFMPQ2-total
0.715
2.889
0.0004
a × b (indirect effect) PCS ⟶ SFMPQ2-total
0.222
2.362
(LL = 0.437, UL = 9.589)
a TSK ⟶ CSI
0.830
0.269
0.00001
b CSI ⟶ SFMPQ2-total
0.390
0.859
0.223
c (direct effect) TSK ⟶ SFMPQ2-total
0.347
1.759
0.277
c′ (total effect) TSK ⟶ SFMPQ2-total
0.671
0.996
0.001
a × b (indirect effect) TSK ⟶ SFMPQ2-total
0.324
1.395
(LL = −0.367, UL = 5.155)
SE, standard error; BC, bias corrected; CI, confidence interval; LL, lower limit; UL, upper limit.
