Clinical Study

Effectiveness of Acupuncture Treatment on Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized, Assessor-Blinded, Controlled Trial

Table 1

Comparison of participants’ baseline demographic and clinical characteristics between two groups.

CharacteristicsAcupuncture (N = 19)Vit B1 and gabapentin (N = 19) value

Age, mean ± SD, years57.95 (10.39)58.79 (8.36)0.79
Gender, no. (%)0.74
 Male7 (36.8)8 (42.1)
 Female12 (63.2)11 (57.9)
Cancer type, no. (%)0.91
 Breast cancer10 (52.6)8 (42.1)
 Lung cancer1 (5.3)0
 Ovarian cancer01 (5.3)
 Prostate cancer1 (5.3)1 (5.3)
 Colorectal cancer
  Colon3 (15.8)5 (26.3)
  Rectum4 (21.1)4 (21.1)
Chemotherapy agents, no. (%)0.93
 Taxane1 (5.3)1 (5.3)
 Platinum compound7 (36.8)9 (47.4)
 Platinum compound-taxane1 (5.3)1 (5.3)
 Doxorubicin/cyclophosphamide-taxane10 (52.6)8 (42.1)
Duration of neuropathy, mean ± SD, month7.16 (7.06)7.47 (5.32)0.88
Number of chemotherapy courses, mean ± SD7.58 (2.63)7.42 (1.98)0.84
Patients symptoms, no. (%)
 Pain0.72
  Yes14 (73.7)13 (68.4)
  No5 (26.3)6 (31.6)
 Numbness
  Yes18 (94.7)18 (94.7)
  No1 (5.3)1 (5.3)
 Paresthesia
  Yes19 (100)19 (100)
  No00
 Subjective impairment in walking0.63
  Yes3 (15.8)2 (10.5)
  No16 (84.2)17 (89.5)

values from between-group comparison using the independent samples test. values from between-group comparisons using the chi-square test.