Effectiveness of Acupuncture Treatment on Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized, Assessor-Blinded, Controlled Trial

Table 2

Comparison of changes of NRS within and between groups over time.

Variables	Time	Acupuncture group (N = 19)		Vit B1 and gabapentin group (N = 19)		Comparison between two groups
		Mean (SD)	value (within-group effect)	Mean (SD)	value (within-group effect)	Difference (95% CI)	value
NRS, marks	Baseline	7.00 (1.53)	<0.001	6.79 (1.47)	<0.001
	2 weeks	5.37 (1.64)		6.32 (1.38)		−1.05 (−1.28 to −0.83)	<0.001
	4 weeks	3.47 (1.61)		5.16 (1.26)		−2.58 (−3.04 to −2.12)	<0.001
	8 weeks	3.68 (1.67)		5.79 (1.32)		−2.16 (−2.64 to −1.68)	<0.001

values from within-group comparison using mixed between-within-subjects analysis of variance (ANOVA). values from pairwise comparisons, adjustment for multiple comparison: least significant difference. NRS = Numerical Rating Scale.