Research Article

Relationship between Pain Behavior and Changes in KCNA2 Expression in the Dorsal Root Ganglia of Rats with Osteoarthritis

Figure 2

Pathological changes in the knee joints. (a) Hematoxylin-Eosin (HE) staining. (b) Safranin O-Fast Green staining. In group C, the articular cartilage surface was smooth and there was no crack formation, the cells were normal and arranged regularly, the tidal line was clear, and there was no bone hyperplasia. In the group OA, with the development of the OA, the destruction of cartilage surface is aggravated and even bone exposure occurred, the increasing exacerbation of cartilage matrix reduction and bone hyperplasia was apparent, the tidal line gradually blurred, and pathological changes showed typical advanced OA manifestations at four to six weeks.
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