VGLUT2/Cdk5/p25 Signaling Pathway Contributed to Inflammatory Pain by Complete Freund’s Adjuvant

Figure 4

VGLUT2 protein expression was markedly increased in the spinal cord and reduced by roscovitine. Compared with the control group by intraplantar injection of saline, VGLUT2 expression was significantly increased from day 1 to day 3 after intraplantar injection of CFA. and ; n = 4/group A. Compared with the controls by intrathecal injection of DMSO, the increased expression of VGLUT2 protein was significantly reduced by intrathecal injection of roscovitine between day 1 and day 3 after intraplantar injection of CFA. Data shown represent mean ± SEM; ; n = 4/group B.

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