TY - JOUR A2 - Kasai, Shinya AU - Eghbal, Mohammad Jafar AU - Haeri, Ali AU - Shahravan, Arash AU - Kazemi, Ali AU - Moazami, Fariborz AU - Mozayeni, Mohammad Ali AU - Saberi, Eshaghali AU - Samiei, Mohammad AU - Vatanpour, Mehdi AU - Akbarzade Baghban, Alireza AU - Fazlyab, Mahta AU - Parhizkar, Ardavan AU - Ahmadi, Mahboobe AU - Akbarian Rad, Nazila AU - Bijari, Shima AU - Bineshmarvasti, Delaram AU - Davoudi, Paria AU - Dehghan, Roya AU - Dehghani, Mandana AU - Ebrahimi, Habibollah AU - Emami, Nafiseh AU - Farajian, Nafiseh AU - Fereidooni, Rahim AU - Ghobadi, Gelareh AU - Ghodrati, Mostafa AU - Gohari, Atefeh AU - Hashemi, Azadeh AU - Hosseini, Mohammadreza AU - Karami, Elham AU - Kheirabadi, Nasir AU - Kozegari, Sepideh AU - Labaf Ghasemi, Hadi AU - Majidi, Alireza AU - Malekzadeh, Parastu AU - Mehrabi, Vahid AU - Mohammadi, Mehrnush AU - Moradi Eslami, Leila AU - Noghani, Atefeh AU - Omatali, Negin AU - Pourhatami, Negar AU - Rahbani Nobar, Behnam AU - Rahmani, Saeid AU - Shafaq, Parviz AU - Soofiabadi, Sara AU - Teimoori, Somaye AU - Vatandoost, Farzaneh AU - Asgary, Saeed PY - 2020 DA - 2020/06/30 TI - Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial SP - 5853412 VL - 2020 AB - This equivalence, randomized, clinical trial aimed to compare the postoperative pain of root canal therapy (RCT) with pulpotomy with mineral trioxide aggregate (PMTA) or calcium-enriched mixture (PCEM) in permanent mature teeth. In seven academic centers, 550 cariously exposed pulps were included and randomly allocated into PMTA (n = 188), PCEM (n = 194), or RCT (n = 168) arms. Preoperative “Pain Intensity” (PI) on Numerical Rating Scale and postoperative PIs until day 7 were recorded. Patients’ demographic and pre-/intra-/postoperative factors/conditions were recorded/analysed. The arms were homogeneous in terms of demographics. The mean preoperative PIs were similar (P=0.998), the mean sum PIs recorded during 10 postoperative intervals were comparable (P=0.939), and the trend/changes in pain relief were parallel (P=0.821) in all study arms. The incidences of preoperative moderate-severe pain in RCT, PMTA, and PCEM arms were 56.5%, 55.7%, and 56.7%, which after 24 hours considerably decreased to 13.1%, 10.6%, and 12.9%, respectively (P=0.578). The time span of endodontic procedures was statistically different; RCT = 69.73, PMTA = 35.37, and PCEM = 33.62 minutes (P<0.001). Patients with greater preoperative pain, symptomatic apical periodontitis, or presence of PDL widening suffered more pain (P=0.002, 0.035, and 0.023, resp.); however, other pre-/intra-/postoperative factors/conditions were comparable. Pulpotomy with MTA/CEM and RCT demonstrate comparable and effective postoperative pain relief. SN - 1203-6765 UR - https://doi.org/10.1155/2020/5853412 DO - 10.1155/2020/5853412 JF - Pain Research and Management PB - Hindawi KW - ER -