Obesity and Multisite Pain in the Lower Limbs: Data from the Osteoarthritis Initiative

Figure 1

The flow of samples from the Osteoarthritis Initiative Study. ^†Participants with symptomatic tibiofemoral knee osteoarthritis at baseline. ^≠Participants with no symptomatic tibiofemoral osteoarthritis in either knee at baseline, but had an elevated risk of developing symptoms of knee osteoarthritis during the study. ^§Participants with no pain, aching, or stiffness in either knee in the past year, along with no radiographic findings of osteoarthritis and no eligibility risk factors. ^¶Data are missing for the variable indicating which knee was eligible for the study. BMI: body mass index.