Lumbar Facet Joint Compressive Injury Induces Lasting Changes in Local Structure, Nociceptive Scores, and Inflammatory Mediators in a Novel Rat Model

<table>Pressure sensitivity measured by algometer in naive (<i>n</i> = 6), sham (<i>n</i> = 6) and model (<i>n</i> = 6) rats at lumbar levels 6, 3/4 and 1. (a) At L6, model animals showed a difference in sensitivity only on day 7 compared to either sham or naïve animals (<i>P</i> &lt; 0.05). (b) At L3/4, model animals showed a higher sensitivity compared to sham animals on days 7 and 28 (<i>P</i> &lt; 0.01) and compared to naïve animals on days 7, 14 and 28 (<i>P</i> &lt; 0.01). (c) At L1, model animals showed a higher sensitivity to pressure on all test days compared to sham and naïve animals (<i>P</i> &lt; 0.001).</table>

Pain Research and Treatment

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Figure 4: Lumbar Facet Joint Compressive Injury Induces Lasting Changes in Local Structure, Nociceptive Scores, and Inflammatory Mediators in a Novel Rat Model 

Figure 4 | Lumbar Facet Joint Compressive Injury Induces Lasting Changes in Local Structure, Nociceptive Scores, and Inflammatory Mediators in a Novel Rat Model 