Figure 1: Glutaminase (GLS) immunoreactivity (ir) in rat L4 dorsal root ganglia (DRG) following 7 days of adjuvant-induced arthritis (AIA) in the hindpaw. DRG sections were processed simultaneously with a rabbit polyclonal GLS antiserum and photographed under identical conditions. (a) In control sections, GLS-IR was light to moderate in all neuronal cell sizes, small (long arrows), and medium to large (short arrows). (b) Elevated GLS-ir in small (long arrows) and medium to large (short arrows) neurons occurred in the DRG following AIA.