Validation of the Self-Assessment of Treatment Questionnaire among Patients with Postherpetic Neuralgia
Table 10
Concurrent validity: ANOVA models of NPRS change scores by SAT scores at Week 12 (pooled dataset; )1.
SAT
NPRS change scores at Week 12
Pain now
Average pain in last 24 hours
N
LS mean (SE)
-value
N
LS mean (SE)
-value
(1) How do you assess your pain level after treatment in this study?
Better
341
−2.5 (0.1)
<0.0001
339
−2.9 (0.1)
<0.0001
No change
310
−0.3 (0.1)
303
−0.5 (0.1)
Worse
47
0.8 (0.3)
46
(0.2)
(2) How do you assess your activity level after treatment in this study?
Better
210
−2.9 (0.1)
<0.0001
209
−3.2 (0.1)
<0.0001
No change
453
−0.7 (0.1)
445
−1.0 (0.1)
Worse
35
0.4 (0.4)
34
−0.1 (0.3)
(3) How has your quality of life changed after treatment in this study?
Better
266
−2.6 (0.1)
<0.0001
265
−3.1 (0.1)
<0.0001
No change
410
−0.6 (0.1)
402
−0.8 (0.1)
Worse
22
1.2 (0.4)
21
(0.4)
(4) Would you undergo this treatment again?
Better
451
−1.8 (0.1)
<0.0001
445
−2.1 (0.1)
<0.0001
No change
174
−0.4 (0.2)
172
−0.8 (0.1)
Worse
73
−0.3 (0.3)
71
−0.5 (0.2)
(5) How do you compare the treatment you received in this study to previous medication or therapies for your pain?
Better
296
−2.2 (0.1)
<0.0001
294
−2.6 (0.1)
<0.0001
No change
312
−0.7 (0.1)
306
−0.9 (0.1)
Worse
90
−0.4 (0.2)
88
−0.8 (0.2)
SAT treatment effect subscale (Items 1, 2, and 3)
Better
359
−2.4 (0.1)
<0.0001
357
−2.8 (0.1)
<0.0001
No change
280
−0.3 (0.1)
273
−0.5 (0.1)
Worse
59
0.9 (0.3)
58
0.2 (0.2)
SAT treatment satisfaction subscale (Items 4 and 5)
Better
448
−1.8 (0.1)
<0.0001
443
−2.1 (0.1)
<0.0001
No change
141
−0.5 (0.2)
138
−0.9 (0.2)
Worse
109
−0.2 (0.2)
107
−0.5 (0.2)
ANOVA: analysis of variance; LS: least-squares; NPRS: Numeric Pain Rating Scale; SAT: Self-Assessment of Treatment; SE: standard error. oncurrent validity was evaluated using ANOVA to compare NPRS changes in pain by SAT response levels (patients improved; no change; worsened). Pooled dataset included data from two clinical trials, Studies C116 () and C117 ().
