Validation of the Self-Assessment of Treatment Questionnaire among Patients with Postherpetic Neuralgia
Table 8
Known-groups validity: ANOVA models of SAT scores by global assessment levels at week 12 (pooled dataset; )1.
SAT at Week 12
n
(1) Pain relief
(2) Activity level
(3) Quality of life
(4) Undergo treatment again
(5) Compared to previous treatment
3-Item SAT treatment effect subscale
2-Item SAT treatment satisfaction subscale
PGIC, LS mean (SE)
Very much improved
103
1.9 (0.0)
1.4 (0.1)
1.7 (0.1)
1.7 (0.1)
1.7 (0.1)
5.0 (0.1)
3.5 (0.2)
Much improved
115
1.4 (0.0)
0.8 (0.1)
1.0 (0.0)
1.6 (0.1)
1.1 (0.1)
3.3 (0.1)
2.7 (0.1)
Slightly improved
159
0.8 (0.0)
0.3 (0.0)
0.5 (0.0)
1.1 (0.1)
0.5 (0.1)
1.6 (0.1)
1.6 (0.1)
No change
275
0.0 (0.0)
0.0 (0.0)
0.0 (0.0)
0.6 (0.1)
0.0 (0.1)
−0.1 (0.1)
0.6 (0.1)
Slightly worse
31
−0.7 (0.1)
−0.3 (0.1)
−0.1 (0.1)
0.0 (0.2)
−0.2 (0.2)
−1.1 (0.2)
−0.2 (0.3)
Much worse2
14
−1.2 (0.1)
−0.9 (0.2)
−0.9 (0.1)
−0.9 (0.3)
−1.1 (0.2)
−3.0 (0.3)
−2.0 (0.4)
-value
<0.0001
<0.0001
<0.0001
<0.0001
<0.0001
<0.0001
<0.0001
CGIC3, LS mean (SE)
Very much improved
63
1.9 (0.1)
1.4 (0.1)
1.7 (0.1)
1.7 (0.1)
1.7 (0.1)
5.0 (0.2)
3.5 (0.2)
Much improved
56
1.4 (0.1)
0.7 (0.1)
1.0 (0.1)
1.3 (0.1)
1.1 (0.1)
3.0 (0.2)
2.4 (0.2)
Slightly improved
78
0.7 (0.1)
0.3 (0.1)
0.5 (0.1)
0.9 (0.1)
0.4 (0.1)
1.5 (0.2)
1.3 (0.2)
No change
140
−0.1 (0.0)
−0.1 (0.1)
−0.1 (0.0)
0.3 (0.1)
−0.2 (0.1)
−0.3 (0.1)
0.1 (0.1)
Slightly worse
10
−0.1 (0.2)
0.1 (0.2)
0.2 (0.2)
−0.2 (0.3)
−0.1 (0.3)
0.2 (0.4)
−0.3 (0.5)
Much worse2
2
−1.5 (0.4)
−0.5 (0.5)
−0.5 (0.4)
−1.5 (0.7)
−0.5 (0.7)
−2.5 (1.0)
−2.0 (1.1)
-value
<0.0001
<0.0001
<0.0001
<0.0001
<0.0001
<0.0001
<0.0001
ANOVA: analysis of variance; CGIC: Clinician Global Impression of Change; LS: least-squares; PGIC: Patient Global Impression of Change; SAT: Self-Assessment of Treatment; SE: standard error. nown-groups validity was assessed using ANOVA to evaluate whether SAT items and subscale scores discriminated between patient groups based on different amounts of patient- and clinician-reported change at Week 12. Pooled dataset included data from two clinical trials, Studies C116 () and C117 (). GIC and CGIC responses of “Very much worse” and “Much worse” were combined due to small sample sizes. tudy C117 only.
