A New Drug Release Method in Early Development of Transdermal Drug Delivery Systems

Table 1

Similarity factors, 𝑓₂, comparing stated release profile and release measured by USP apparatus 5 and SSS method.

	12 𝜇g/hr Durogesic patch		75 𝜇g/hr Durogesic patch
	USP apparatus	SSS method	USP apparatus	SSS method
𝑓2 value	4.46	63.89	1.54	77.01