Estrogen and Visceral Nociception at the Level of Primary Sensory Neurons
Figure 1
Models of alternative possibilities for viscero-visceral cross-sensitization in the DRG neuron. (a) ATP released by a neuron innervating the inflamed uterus acts on a neighboring neuron sensitizing its responses to colonic distention. (b) The same neuron innervates the uterus and colon. Uterus inflammation directly sensitizes the neuron to colonic distention.
