Pain Research and Treatment / 2014 / Article / Tab 7

Research Article

Clinical Characteristics, Patient-Reported Outcomes, and Previous Therapeutic Management of Patients with Uncontrolled Neuropathic Pain Referred to Pain Clinics

Table 7

Pharmacological treatment, reasons for uncontrolled pain, and treatment satisfaction by clinical entity.

CharacteristicDiabetic neuropathy Other neuropathies Trigeminal neuralgia Other neuralgia Radiculopathy Nerve entrapment syndrome Plexopathy Complex regional pain syndrome Postsurgery/trauma Oncological pain Central neuropathic pain

VAS, mean ± SD
WHO-DAS II Interference with life (severe/extreme), %52.052.742.939.146.738.352.467.733.430.466.7
Number of previous treatments, mean ± SD
Treatment at the time of inclusion, %
Paracetamol17.45.66.323.832.028.622.720.025.520.910.0
NSAIDs17.433.321.947.649.648.640.948.644.722.010.0
Opiods34.827.828.123.844.945.750.037.127.731.950.0
 Tramadol21.722.228.114.333.534.345.525.714.924.235.0
 Others13.011.13.19.515.114.318.220.012.813.230.0
AED52.272.290.647.645.642.945.554.336.270.385.0
 Pragabalin26.138.925.014.328.314.327.331.419.124.235.0
 Gabapentin30.433.331.319.016.925.718.211.417.038.560.0
 Carbamazepine/ oxcarbazepine0.00.056.314.31.10.04.55.70.012.110.0
 Other4.35.612.50.02.62.90.05.70.06.620.0
Antidepressants17.422.218.819.016.214.345.528.614.923.120.0
 Duloxetine8.75.60.04.86.62.90.05.74.35.55.0
 Tricyclics8.722.215.69.55.98.631.820.08.516.55.0
 Other0.00.03.14.84.45.713.65.72.11.110.0
Other drugs34.844.443.852.450.037.140.937.144.748.455.0
Causes for uncontrolled pain, %
Misdiagnosis15.418.23.112.58.410.320.811.127.89.14.8
Nonoptimized treatment80.877.378.183.391.289.795.886.177.887.985.7
 Use of ineffective drugs61.929.420.045.048.757.139.148.469.036.811.1
 Subtherapeutic dose47.641.252.025.046.140.043.538.728.657.555.6
 Other9.541.244.040.024.417.130.425.819.021.850.0
Lack of compliance15.44.50.012.56.17.74.211.11.95.19.5
Intolerance0.09.112.54.27.75.14.22.83.76.119.0
Other11.59.112.54.26.40.00.05.67.410.19.5
SATMED-Q
Total score, mean ± SD
Efficacy, mean ± SD

AED: antiepileptic drugs; NSAIDs: nonsteroidal anti-inflammatory drugs; SATMED-Q: Treatment Satisfaction with Medicines Questionnaire; SD: standard deviation; VAS: visual analog scale; WHO-DAS II: World Health Organization Disability Assessment Schedule II; Yrs: years.

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