Pain Research and Treatment / 2014 / Article / Tab 4

Review Article

Perioperative Multimodal Anesthesia Using Regional Techniques in the Aging Surgical Patient

Table 4

Changes in the aging central nervous system
 (i) Decreased synaptic transmission
 (ii) Diffuse slowing on EEG
 (iii) Decreased oxygen and glucose consumption
 (iv) Loss of neuronal substance
 (v) Decreased production of neurotransmitters
 (vi) Decrease in cytoplasmic protein synthesis
 (vii) Decreased myelin glycoproteins

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