Coadministration of Resveratrol and Rice Oil Mitigates Nociception and Oxidative State in a Mouse Fibromyalgia-Like Model

Figure 5

Assessment of chronic treatment with RSV, RSV + RO, or PGB on the open field test in the fibromyalgia model in mice. The exploratory ability of the mice, crossing (a) and rearing (b), was tested on the 4th day after onset of reserpine injection (0.25 mg/kg, s.c., once a day for 3 days) and after the onset of the oral administration of its corresponding treatment (once a day for 4 days). Data are presented as mean ± SEM. compared to control (SAL-SAL). Statistical analysis was performed by one-way ANOVA followed by Bonferroni’s post hoc test. (a and b) to 10 mice/group.

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(b)