Coadministration of Resveratrol and Rice Oil Mitigates Nociception and Oxidative State in a Mouse Fibromyalgia-Like Model

Figure 8

Chronic treatment with RSV, RSV + RO, RO, or PGB reduces ROS production in the CSF of reserpine-treated mice in the fibromyalgia model. ROS production was measured in the CSF of reserpine-injected mice after the treatment with RSV, RSV + RO, RO, or PGB (once a day for 4 days). Data are presented as mean + SEM. compared to control (SAL-SAL), , compared to RES-SAL group. Statistical analysis was performed by one-way ANOVA followed by Bonferroni’s post hoc test. mice/group.