Research Article

The Effectiveness of Aromatherapy in Reducing Pain: A Systematic Review and Meta-Analysis

Table 1

Studies included in analysis. A summary of the studies included in analysis. CRP = C-reactive protein; VAS = visual analog score; WBC = white blood count.

StudyStudy designParticipants (diagnosis, )InterventionComparisonSummary of results

Ayan et al., 2013Randomized controlled trial, double blindRenal colic, 80Rose oil in vaporizer and conventional treatmentPlacebo and conventional treatmentThere was no statistically significant difference between the starting VAS values of the two groups, but the VAS values 10 or 30 minutes after the initiation of therapy were statistically lower in the group that received conventional therapy plus aromatherapy.

Bagheri-Nesami et al., 2014Randomized controlled trialHemodialysis, 88Inhaled lavender oil during hemodialysis treatmentPlaceboThe mean VAS pain intensity score in the experimental and control groups before the intervention was 3.78 + 0.24 and 4.16 + 0.32, respectively (). The mean VAS pain intensity score in the experimental and control groups after three aromatherapy sessions was 2.36 + 0.25 and 3.43 + 0.31, respectively ().

Hadi and Hanid, 2011Clinical trial, single blindCesarean section, 200Lavender oil in face mask with oxygenPlaceboThe aromatherapy group experienced a significant decrease in pain compared to the control group.

Jun et al., 2013Randomized controlled trialPostoperative knee replacement, 25Inhalation of eucalyptus on gauzePlaceboPain VAS on all three days () and systolic () and diastolic () blood pressure on the second day were significantly lower in the group inhaling eucalyptus than that inhaling almond oil. Heart rate, CRP, and WBC, however, did not differ significantly in the two groups.

Kaviani et al., 2014Clinical trial, semi-experimentalLabor pain, 160Lavender oil on swab attached to patientPlaceboThe mean of pain intensity perception in the aroma group was lower than that of the control group at 30 and 60 minutes after the intervention ().

Martin, 2006 [4]Randomized controlled trialHand in ice water, 60Lemon in oil diffuserMachine oil in diffuser, no odorIndividuals exposed to both odors reported significantly greater pain than did those in the control condition at 5 minutes. At 15 minutes, individuals exposed to the unpleasant odor experienced greater pain than did the control group.

Marzouk et al., 2013Randomized controlled trialMenstrual pain, 95Abdominal aromatherapy massageAbdominal massage onlyDuring both treatment phases, the level and duration of menstrual pain and the amount of menstrual bleeding were significantly lower in the aromatherapy group than in the placebo group.

Ou et al., 2012 [5]Randomized controlled trial, double-blindMenstrual pain, 48Self-massage with lavender, clary sage, and marjoramPlaceboPain was significantly decreased () after one menstrual cycle intervention in the two groups. The duration of pain was significantly reduced from 2.4 to 1.8 days after aromatherapy intervention in the essential oil group.

Sheikhan et al., 2012Randomized controlled trialEpisiotomy, 120Lavender oil in sitz bath on effected areaTreatment as usualThere was a statistical difference in pain intensity scores between the 2 groups after 4 hours (), and 5 days () after episiotomy. However, differences in pain intensity between the two groups, at 12 hours after surgery, were not significant ().

Yip et al., 2004Randomized controlled trialLow back pain, 51Acupoint stimulation for relaxation with electrode pads followed by an acupressure massageTreatment as usual8 sessions of acupoint stimulation followed by acupressure with aromatic lavender oil were an effective method for short-term low back pain relief.

Yip and Tse, 2006 [6]Experimental studyNeck pain, 28Acupressure with lavender oilTreatment as usualThe baseline VAS for the intervention and control groups were 5.12 and 4.91 out of 10, respectively (). One month after the end of treatment, compared to the control group, the manual acupressure group had 23% reduced pain intensity ().