Preemptive Analgesia in Total Knee Arthroplasty: Comparing the Effects of Single Dose Combining Celecoxib with Pregabalin and Repetition Dose Combining Celecoxib with Pregabalin: Double-Blind Controlled Clinical Trial

Table 3

VAS measurement among the groups after undergoing TKA procedure evaluated from the first day until the third day.

	VAS D-1	VAS D-2	VAS D-3	P value
	N=10	N=10	N=10
Group 1 (1 hr preemptive analgesia)	2 (2-3)	1 (1-2)	1 (1-2)	<0.001
Group 2 (72 hrs preemptive analgesia)	2.5 (2-3)	2 (1-2)	1.2 (1-2)	0.001
Group 3 (Placebo)	4(2-5)	3 (2-4)	3 (2-3)	0.001

The data were not normally distributed.
The p value was measured using Kruskal-wallis nonparametric test.