Incidence and Health Related Quality of Life of Opioid-Induced Constipation in Chronic Noncancer Pain Patients: A Prospective Multicentre Cohort Study
Table 1
General characteristics of CNCP patients at baseline.
Variable
No Constipation
Constipation
Total
674 (100%)
500 (74.2%)
174 (25.8%)
Age, years
18-45
151
110 (22.0%)
41 (23.6%)
45-60
214
162 (32.4%)
52 (29.9%)
60-75
221
169 (33.8%)
52 (29.9%)
>75
88
59 (11.8%)
29 (16.7%)
Gender
Female
488
357 (71.4%)
131 (75.3%)
Male
186
143 (28.6%)
43 (24.7%)
BMI
27.0 (±5.20)
27.1 (±5.20)
26.5 (±5.20)
Education level
No education
19
12 (2.4%)
7 (4.0%)
1-4 years (basic 1st cycle)
340
246 (49.2%)
94 (54.3%)
5-9 years (basic 2nd and 3rd cycles)
163
127 (25.4%)
36 (20.8%)
10-12 years (secondary)
78
60 (12.0%)
18 (10.4%)
More than 12 years(higher)
73
55 (11.0%)
18 (10.4%)
Opioid therapy
402
228 (56.7%)
174 (43.2%)
Analgesic prescription
Non-opioid
213
163 (32.6%)
50 (28.7%)
Weak opioid
339
229 (45.8%)
110 (63.2%)
Strong opioid
126
62 (12.4%)
64 (36.8%)
Laxatives use
24
12 (15.8%)
12 (30.8%)
Current depressive disorder on treatment
139
97 (20.8%)
42 (25.8%)
OIC: opioid-induced constipation; BMI: body mass index; data are presented as (%) except BMI which is presented as mean ± standard deviation. Proportions are calculated as column proportions.
