Incidence and Health Related Quality of Life of Opioid-Induced Constipation in Chronic Noncancer Pain Patients: A Prospective Multicentre Cohort Study
Table 4
Pain characteristics.
Pain Characteristics
Baseline
6 Months
Total
No constipation
Constipation
P value
No Constipation
Constipation
P value
Pain duration
Pain duration in years
4.0 (2.0-12.0)
4.0 (2.0-13.0)
5.0 (2.0-10.5)
0.207
4.0 (2.0-12.0)
4.7 (2.0-14.0)
0.782
Pain location
Head
67 (65.0%)
67 (65.0%)
36 (35.0%)
0.021
69 (67.0%)
34 (33.0%)
0.931
Face
26 (61.9%)
26 (61.9%)
16 (38.1%)
0.060
28 (66.7%)
14 (33.3%)
0.921
Cervical region
172 (68.5%)
172 (68.5%)
79 (31.5%)
0.010
156 (62.2%)
95 (37.8%)
0.028
Dorsal region
41 (64.1%)
41 (64.1%)
23 (35.9%)
0.052
46 (71.9%)
18 (28.1%)
0.485
Lumbar region
292 (73.7%)
292 (73.7%)
104 (26.3%)
0.324
265 (66.9%)
131 (33.1%)
0.803
Abdominal region
21 (73.8%)
21 (73.8%)
11 (26.2%)
0.954
28 (66.7%)
14 (33.3%)
0.921
Upper Limb
240 (70.4%)
240 (70.4%)
101 (29.6%)
0.022
226 (66.3%)
115 (31.5%)
0.566
Lower Limb
314 (72.5%)
314 (72.5%)
119 (27.5%)
0.185
294 (67.9%)
139 (33.6%)
0.732
Pain aetiology
Chronic primary pain
50 (7.4%)
32 (64.0%)
18 (36.0%)
0.087
18 (43.9%)
23 (56.1%)
0.008
Chronic postsurgical and posttraumatic pain
92 (13.6%)
66 (71,7%)
26 (28.3%)
0.564
47 (62.7%)
28 (37.3%)
0.813
Chronic neuropathic pain
170 (25.2%)
128 (75.3%)
42 (24.7%)
0.702
99 (67.8%)
47 (32.2%)
0.926
Chronic headache and orofacial pain
15 (2.2%)
6 (40.0%)
9 (60.0%)
0.002
7 (58.3%)
5 (41.7%)
0.581
Chronic visceral pain
26 (3.9%)
15 (57.7%)
11 (42.3%)
0.050
14 (63.6%)
8 (36.4%)
0.833
Chronic musculoskeletal pain
254 (37.7%)
183 (72%)
71 (28.0%)
0.324
249 (69.9%)
107 (30.1%)
0.310
Data are presented as (%) except pain duration which is presented as median (interquartile range). Proportions are calculated as row proportions. values are derived from (a) comparisons; (b) test; (c) Mann-Whitney test.
