Therapeutic Options of Chondrodermatitis Nodularis Helicis

Table 2

Physical therapies.

First author and year	Number of patients	Method	Cure rate	Follow-up; (mean)	Recurrence rate	Pros and cons
Photodynamic therapy (PDT)
Pellegrino 2011 [37]	2	PDT	100%	9 months	0	Case report.
Gilaberte 2010 [30]	5	PDT + curretage	80%	Not reported	Not reported	Retrospective, confounder with curettage, follow-up not reported.
Cryotherapy
Senel 2010 [47]	1	Cryotherapy 2	100%	12 months	0	Case report.
Argon laser
Hesse 1994 [18]	9 pts/16 lesions	Biopsy + argon laser for surface and underlying cartilage	56%	3–16 months	“No real recurrence” (4 patients with recurrence after 3–16 months, retreated)	Prospective.
CO2 laser
Taylor 1991 [19]	11 pts/12 lesions	CO2 laser to vaporize the cutaneous nodule and involved cartilage + decompression for 3-4 weeks	100%	2–15 months	0	Prospective. Confounder with decompression.
Karam 1988 [38]	3	CO2 laser at 15 W	100%	24 months	0	Case series.
Curettage/electrocauterization
Kromann 1983 [21]	142	Curettage followed by electrocauterization	69%	7,1 years (average)	31%	Retrospective. Confounder with many other therapies.