Research Article
Psychiatric Axis I Comorbidities among Patients with Gender Dysphoria
Table 1
Prevalence rates of lifetime DSM Axis I psychiatric comorbidities in patients.
| | Total (83) | Male-to-female |
Female-to-male | | | | % | | % | | % |
| Major depressive disorder | 28 | 33.7 | 17 | 36.2 | 11 | 30.6 | 0.287* | 0.592 | Dysthymic disorder | 6 | 7.2 | 3 | 6.4 | 3 | 8.3 | 0.116* | 0.734 | Minor depressive disorder | 5 | 6 | 3 | 6.4 | 2 | 5.6 | 0.025** | 1.000 | Bipolar I disorder | 1 | 1.2 | 1 | 2.1 | — | — | 0.775** | 1.000 | Bipolar II disorder | 1 | 1.2 | 1 | 2.1 | — | — | 0.775** | 1.000 | Mood disorder (total) | 36 | 43.4 | 23 | 48.9 | 13 | 36.1 | 1.365* | 0.243 |
| Specific phobia | 17 | 20.5 | 8 | 17 | 9 | 25.0 | 0.797* | 0.372 | Obsessive-compulsive disorder | 5 | 6 | 4 | 8.5 | 1 | 2.8 | 1.183** | 0.382 | Generalized anxiety disorder | 5 | 6 | 3 | 6.4 | 2 | 5.6 | 0.025** | 1.000 | Social phobia | 4 | 4.8 | 2 | 4.3 | 2 | 5.6 | 0.075** | 1.000 | Panic disorder without agoraphobia | 4 | 4.8 | 2 | 4.3 | 2 | 5.6 | 0.075** | 1.000 | Posttraumatic stress disorder | 2 | 2.4 | 2 | 4.3 | — | — | 1.570** | 0.503 | Anxiety disorder (total) | 30 | 36.1 | 18 | 38.8 | 12 | 33.3 | 0.218* | 0.641 |
| Adjustment disorder | 13 | 15.7 | 6 | 12.8 | 7 | 19.4 | 0.688* | 0.407 |
| Alcohol abuse | 4 | 4.8 | 1 | 2.1 | 3 | 8.3 | 1.711** | 0.312 | Nicotine dependence | 3 | 3.6 | 1 | 2.1 | 2 | 5.6 | 0.688** | 0.576 | Sedative, hypnotic, or anxiolytic abuse | 2 | 2.4 | 1 | 2.1 | 1 | 8 | 0.037** | 1.000 | Cannabis abuse | 1 | 1.2 | 1 | 2.1 | — | — | 0.775** | 1.000 | Amphetamine abuse | 1 | 1.2 | 1 | 2.1 | — | — | 0.775** | 1.000 | Substance use disorder (total) | 7 | 8.4 | 3 | 6.4 | 4 | 11.1 | 0.590* | 0.442 |
| Axis I psychiatric disorder (total) | 52 | 62.7 | 31 | 66 | 21 | 68.3 | 0.506* | 0.477 |
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*Chi square **Fisher’s exact test.
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