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Rehabilitation Research and Practice
Volume 2011, Article ID 497690, 6 pages
http://dx.doi.org/10.1155/2011/497690
Clinical Study

Improved Left Ventricular Diastolic Function with Exercise Training in Hypertension: A Doppler Imaging Study

Tongji Hospital, Tongji University, 389 Xincun Road, Shanghai 200065, China

Received 25 September 2010; Revised 23 November 2010; Accepted 3 January 2011

Academic Editor: Luc Vanhees

Copyright © 2011 Huan Zheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To study the effects of 6 months’ exercise training on ventricular function in hypertensive patients. Methods. Both groups received routine anti-hypertensive pharmacological therapy and one received a 6 months’ exercise program in addition. All patients underwent incremental cardiopulmonary exercise test and echocardiography in baseline and after 6 months. Results. (1) In 6 months’ follow-up, PeakVO2, Powermax (max workload), AT (anaerobic threshold), VO2AT (VO2 at anaerobic threshold), tAT (time from beginning to anaerobic threshold) ( 𝑃 < . 0 5 ), were increased in the exercise group. HRrest (Heart rate at rest) was decreased ( 𝑃 < . 0 5 ). LAVI (left atrial volume index), peak mitral filling velocities during early (E) and late (A) diastole E/A ratio, DT(deceleration time of the mitral E wave), IVST(Interventricular septum thickness in diastole), tissue Doppler indice Mean Ea/Aa ratio ( 𝑃 < . 0 5 ) were also improved. (2) Correlation analysis: 4 variates had significant effect on change of PeakVO2 in the exercise group: age ( 𝑟 = 0 . 3 9 ), change of HRrest ( 𝑟 = 0 . 5 9 ), change of E/A ( 𝑟 = 0 . 5 5 ), change of Mean Ea/Aa ( 𝑟 = 0 . 5 8 ); Through analyzing 2 groups patients’ baseline values, their age ( 𝛽 = 0 . 3 2 ), VO2AT ( 𝛽 = 0 . 2 9 ), HRrest ( 𝛽 = 0 . 2 5 ), LAVI ( 𝛽 = 0 . 2 4 ), E/A ( 𝛽 = 0 . 4 1 ) were found to be independent predictors of MeanEa/Aa. 𝑃 -value under .05 was considered statistically significant. Conclusion. 6 months’ exercise could enhance hypertensive patients’ aerobic exercise level and diastolic function to a certain extent.