Rehabilitation Research and Practice / 2011 / Article / Tab 1

Clinical Study

Treatment of Fatigue in Multiple Sclerosis Patients: A Neurocognitive Approach

Table 1

Mean clinical variable scores at baseline and after five weeks of treatment ( 𝑛 = 2 0 ).

VariableBaseline mean (SD)First follow-up mean (SD) 𝑃

EDSS2.45 (1.29)2.48 (1.26)N.S.

FSS5.66 (0.48)4.20 (1.07)<0.0001

MFIS36.50 (14.28)23.80 (12.40)<0.0001
 pMFIS20.15 (6.33)13.45 (6.68)<0.0001
 cMFIS14.15 (8.36)8.55 (6.16)<0.0001
 psMFIS2.20 (2.12)1.70 (1.53)0.133

MSFC0.10 (0.61)0.21 (0.56)0.035
 NHPT22.04 (5.73)21.04 (4.34)0.083
 25FWT5.83 (1.78)5.58 (1.94)0.093
 PASAT39.55 (12.09)41.65 (13.19)0.095

MSQOL-54
 PHCS52.46 (17.08)65.17 (15.98)0.002
 MHCS60.78 (16.80)70.48 (16.33)0.004

EDDS: Expanded Disability Status Scale, MSFC: Multiple Sclerosis Functional Composite, NHPT: Nine-Hole Peg Test, 25 FWT: 25-Foot Walking Test, PASAT: Paced Auditory Serial Addition Test, FSS: Fatigue Severity Scale, MFIS: Modified Fatigue Impact Scale, pMFIS: physical MFIS subscale, cMFIS: cognitive MFIS subscale, psMFIS: psychosocial MFIS subscale, MSQOL-54: Multiple Sclerosis Quality of Life Questionnaire, PHCS: Physical Health Composite Score, MHCS: Mental Health Composite Score.