Treatment of Fatigue in Multiple Sclerosis Patients: A Neurocognitive Approach

Table 2

Mean clinical variables scores at baseline and 6 months after treatment (𝑛=18).

Variable	Baseline; mean (SD)	Second follow-up; mean (SD)	𝑃
EDSS	2.50 (1.34)	2.53 (1.63)	N.S.
FSS	5.72 (0.47)	4.17 (1.31)	<0.0001
MFIS	36.67 (13.76)	26.78 (17.65)	0.010
pMFIS	20.28 (6.35)	15.71 (8.87)	0.025
cMFIS	14.33 (8.20)	9.72 (8.50)	0.009
psMFIS	2.06 (2.01)	1.33 (1.81)	0.054
MSFC	0.10 (0.63)	0.22 (0.64)	0.122
NHPT	22.21 (5.96)	20.97 (4.44)	0.220
25FWT	5.80 (1.83)	5.77 (2.57)	0.108
PASAT	39.56 (12.45)	41.89 (14.41)	0.216
MSQOL-54
PHCS	52.80 (16.64)	60.78 (17.80)	0.049
MHCS	61.19 (15.56)	65.03 (18.48)	0.309

EDDS: Expanded Disability Status Scale, MSFC: Multiple Sclerosis Functional Composite, NHPT: Nine-Hole Peg Test, 25 FWT: 25-Foot Walking Test, PASAT: Paced Auditory Serial Addition Test, FSS: Fatigue Severity Scale, MFIS: Modified Fatigue Impact Scale, pMFIS: physical MFIS subscale, cMFIS: cognitive MFIS subscale, psMFIS: psychosocial MFIS subscale, MSQOL-54: Multiple Sclerosis Quality of Life Questionnaire, PHCS: Physical Health Composite Score, MHCS: Mental Health Composite Score.