Clinical Study

White Matter Atrophy in Patients with Mesial Temporal Lobe Epilepsy: Voxel-Based Morphometry Analysis of T1- and T2-Weighted MR Images

Table 2

Areas with WM atrophy in patients with left HA, from T1-weighted analysis.

Left atrophy T1
Number clusters (unc) , , Areas

101294
7.47<0.0001−20, −33, 12 Left and right frontal lobes, corpus callosum, left and right cerebellum, thalamus, left and right hippocampus, left and right parahippocampal gyrus, left and right caudate, left and right insula, medulla, left amigdale
7.01 <0.0001−26, −33, 2
6.47<0.0001−4, −11, 17
68 3.69<0.0001−46, 42, −12Right frontal inferior orbital gyrus, middle frontal gyrus, inferior frontal gyrus
146 3.60<0.0001−9, 51, 15 Right medial frontal gyrus, frontal superior medial, cingulum anterior, superior frontal gyrus.
58 3.51<0.00018, 46, 21Left medial frontal gyrus, frontal medial superior gyrus