Gestational Trophoblastic Disease: A Multimodality Imaging Approach with Impact on Diagnosis and Management

Table 1

(a) FIGO 2000 classification for GTN-staging system. (b) FIGO 2000 classification for GTN-risk scoring system.

(a)

Stage I	Disease confined to the uterus.
Stage II	GTN extends outside the uterus but is limited to the genital structures (adnexa, vagina, and broad ligament).
Stage III	GTN extends to the lungs, with or without known genital tract involvement.
Stage IV	All other metastatic sites.

Source: FIGO Oncology Committee (2003) [10].

(b)

Score	0	1	2	4
Age (years)	<40	≥40	—	—
Antecedent pregnancy	Mole	Abortion	Term	—
Interval months from index pregnancy	<4	4–<7	7–<13	≥13
Pretreatment serum 𝛽-hCG (iu/mL)	<10^3	10^3--<10^4	10^4--<10^5	≥10^5
Largest tumor size (cm) (including uterus)	<3	3–<5	≥5	—
Site of metastases	Lung	Spleen, kidney	Gastrointestinal	Liver, brain
Number of metastases	—	1–4	5–8	>8
Previous failed chemotherapy	—	—	Single drug	Two or more drugs

Source: FIGO Oncology Committee (2003) [10].