Mechanical Recanalization following i.v. Thrombolysis: A Retrospective Analysis regarding Secondary Hemorrhagic Infarctions and Parenchymal Hematomas

Table 2

Comparison to other studies.

	Present study	Hacke et al. [13]	Smith et al. [15]	Smith et al. [7]	Penumbra Pivotal Stroke Trial [6]	Nelles et al. [23]	MR CLEAN [20]
(100%)	31	406	141	164	125	65	500
Target vessel	ICA, MCA	ICA, MCA	ICA, MCA, VA, BA	ICA, MCA, VA, BA	ICA, MCA, VA, BA	ICA, MCA	ICA, MCA, ACA
i.v. thrombolysis with rtPA	31 (100%)	406 (100%)	No	48 (29%)	n/a^#	n/a	445 (89%)
Mechanical recanalization	31 (100%)	no	141 (100%)	164 (100%)	125 (100%)	65 (100%)^##	195 (39%)
Hematoma	6 (19.4%)	120 (29.5%)	50 (35.5%)	16 (9.8%)	35 (28%)	3 (5%)^##	35 (7%)

i.v. and also i.a. thrombolysis.
^#Only the percentage of i.v. rtPA in case of bleeding, not the overall i.v. rtPA rate.
^##Only TICI 2b and TICI 3, where they administered only 50% of the usual dose.