Solid Indeterminate Pulmonary Nodules Less Than or Equal to 250 mm³: Application of the Updated Fleischner Society Guidelines in Clinical Practice

Table 5

Association between nodule outcome and independent variables (sex, risk status, volume, margins, and lobe location).

Independent variables	Nodule Outcome		Chi-square test
	Stable ≥ 2 years	Malignant	p value
Sex
Male	13 (48.1)	2 (7.4)	0.447
Female	9 (33.3)	3 (11.1)
Risk status
Low risk	16 (59.3)	-	0.003
High risk	6 (22.2)	5 (18.5)
Volume
< 100 mm^3	14 (51.9)	2 (7.4)	0.340
100-250 mm^3	8 (29.6)	3 (11.1)
Margins
Smooth	19 (70.4)	2 (7.4)	0.009
Lobulated	3 (11.1)	2 (7.4)
Spiculated	-	1 (3.7)
Lobe location
Middle/Lower	13 (48.1)	1 (3.7)	0.121
Upper	9 (33.3)	4 (14.8)

Data are presented as numbers (%).
Chi-squared test for trend.