Review Article

Preoperative Portal Vein Embolization in Hepatic Surgery: A Review about the Embolic Materials and Their Effects on Liver Regeneration and Outcome

Table 1

Embolization Materials reported for portal vein embolization.

PVE materialNo. of studiesNo. of patientsDHFLR absolute growth

Gelatin sponge93558.5% up to 11%17% up to 37%
PVA43259.6% up to 10%24% up to 45%
PVA/microspheres plus coils/VP138698.6% up to 11%27% up to 57%
Ethanol338210.8% up to 12%33.6% up to 40%
Fibrin glue316110%27% up to 31%
NBCA195839% up to 13%27% up to 74%
EVOH24010% up to 14%53%
Ethibloc23410% up to 11%25% up to 61%
Aethoxysklerol/air-foam2307.4% up to 8.5%NR

PVE: portal vein embolization; PVA: polyvinyl-alcohol particles; DH: degree of hypertrophy; VP: vascular plug; NR: not reported; NBCA: n-butyl-cyanoacrylate; EVOH: ethylene vinyl alcohol; One publication reported gelatin sponge associated with other embolic material. Two publications reported also other materials for PVE in the same study. One publication reported 69% hypertrophy, but it was in patients submitted to right PVE plus segment IV. One study mixed NBCA with gelatin sponge and two studies used a vascular plug for central occlusion.