Early Radiologic Diagnosis of Pulmonary Infection in Febrile Neutropenic Patients: A Comparison of Serial Chest Radiography and Single CT Chest

Figure 1

Images in a 58-year-old male patient with acute myeloid leukemia who had positive chest symptoms. (A) Baseline chest film shows right lower lung opacity. (B) Chest film on first day of febrile neutropenia (ANC = 0 μL) shows new opacity at right upper lung and left retrocardiac region. (C) Chest film on the fifth day of febrile neutropenia (ANC = 624 μL) shows stable opacities at right upper and left lower lungs. (D–F) Axial and coronal CT chest on third day of febrile neutropenia (ANC = 432 μL) reveals pulmonary consolidation at right upper lobe and a nodular lesion at left lower lobe. Both lesions are surrounded by a halo of ground-glass attenuation, suggesting angioinvasive pulmonary aspergillosis. This case was evaluated as true-positive chest radiograph and CT chest.